deactivate

verb

de·​ac·​ti·​vate (ˌ)dē-ˈak-tə-ˌvāt 

deactivated; deactivating; deactivates

transitive verb

: to make inactive or ineffective

deactivate a bomb

deactivate a chemical compound

deactivation

(ˌ)dē-ˌak-tə-ˈvā-shən 

noun

deactivator

(ˌ)dē-ˈak-tə-ˌvā-tər 

noun

Synonyms

• kill
• brake
• shut off

Examples of deactivate in a Sentence

deactivate the machine carefully, or you'll risk an electric shock

Recent Examples on the Web

Following the incident, the country star deactivated his X account and apologized to Swift fans for his tweet. —Janelle Ash, FOXNews.com, 7 Oct. 2025

His co-workers then rushed to deactivate the machine and pull him free. —Georgina Jedikovska, Interesting Engineering, 7 Oct. 2025

His TikTok page appears to have been deactivated. —Luke Chinman, PEOPLE, 7 Oct. 2025

Once stationary, deactivate all lights except the hazard flashers, engage the emergency brake, and release the brake pedal to ensure your tail lights are not illuminated, reducing the risk of other drivers colliding with your stationary vehicle. —Nc Weather Bot, Charlotte Observer, 7 Oct. 2025

Word History

First Known Use

1926, in the meaning defined above

Rhymes for deactivate

• abbreviate
• accelerate
• accommodate
• accumulate
• acuminate
• adjudicate
• adulterate
• affiliate
• agglomerate
• agglutinate
• alleviate
• amalgamate

Kids Definition

deactivate

verb

de·​ac·​ti·​vate (ˈ)dē-ˈak-tə-ˌvāt 

: to make inactive or ineffective

deactivation

(ˌ)dē-ˌak-tə-ˈvā-shən 

noun

Medical Definition

deactivate

transitive verb

de·​ac·​ti·​vate (ˈ)dē-ˈak-tə-ˌvāt 

deactivated; deactivating

1

: to make inactive or ineffective

2

: to deprive of chemical activity

deactivate an enzyme

deactivation

-ˌak-tə-ˈvā-shən 

noun